Abuja, Nigeria — Leaders in Africa say the fight against malaria on the continent is facing significant funding gaps due to the ongoing global financial crisis and the impact of climate change.

African leaders this week met in New York on the sidelines of the United Nations General Assembly and called for a concerted effort to avert a funding crisis they say could set back decades of progress in the fight against malaria.

The African Leaders Malaria Alliance, or ALMA, which hosted the high-level meeting, said if malaria funding continues to shrink, there will be an expected additional 112 million cases and some 280,000 deaths by the year 2029.

Africa already accounts for an estimated 236 million malaria cases — or 95% of the global total — and 97% of deaths. Nigeria accounts for nearly a third of that burden.

Guinea-Bissau President Umaro Sissoco Embalo, who serves as chair of ALMA, said that Africa stands at a critical moment in the fight against malaria.

“We must act urgently to protect lifesaving malaria intervention,” he said. “This is very important because our target is to finish with malaria in Africa.”

Experts said Africa needs up to $6.3 billion in malaria funding annually to eliminate the disease and called for continued support for malaria financing within the global funding framework.

ALMA also said the impact of climate change and growing resistance to insecticide and antimalarials are further hampering progress against the disease in Africa.

Ngashi Ngongo, head of the Executive Office at the Africa Union, said, “Achieving the elimination of malaria alongside progress toward other endemic diseases such as HIV and TB will lay the foundation for reducing Africa’s disease burden and further propel the achievement of universal health coverage on the continent.

“This progress is essential for strengthening health systems, and it is a necessity as we prepare for future pandemics, which are inevitable,” he said.

Following the World Health Organization’s approval last year, the first malaria vaccines are being introduced into routine child immunization schedules across Africa.

And on Thursday in New York, Nigerian health authorities signed a deal with U.S.-based drone company Zipline to use artificial intelligence-powered drones to expand access to medical supplies, including blood and vaccines.

Abdu Muktar, who is the national coordinator of Nigeria’s Unlocking Healthcare Value-Chain Initiative, commended the “very bold agenda” for producing health care products locally.

“But now we also have to be able to deliver,” he said. “What Zipline is doing is using technology to make sure you deliver. You’ll be able to reduce wastage in whatever it is — vaccines, therapeutics. You’ll be able to be accountable. … You are able to reach more people.”

In 2022, governments of malaria-endemic countries contributed about $1.5 billion toward combatting the disease.

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